Volume 3, Issue 5, September 2015, Page: 100-103
Histop Athological Comparision of Mast Cell Density in Various Grades of Mucoepidermoid Carcinoma
Farzad Yazdani, Amir Alam Hospital Tehtran University of Medical Sciences, Tehran, Iran
Gita Rezvani, Shahed University, Dentistry School, Tehran, Iran
Sajad Safari, Shahed University, Dentistry School, Tehran, Iran
Maryam Jaberi, Tehran University of Medical School, Tehran, Iran
Received: Jul. 22, 2015;       Accepted: Aug. 7, 2015;       Published: Aug. 21, 2015
DOI: 10.11648/j.crj.20150305.12      View  4048      Downloads  105
Mucoepidermoid carcinoma (MEC) is one of most prevalent carcinomas of salivary glands in which the histoathological grading is very important in treatment and prognosis. In this study we are going to compare mast cell density in different kinds of mucoepidermoid grading by Toluidine blue staining. Materials and Methods. Paraffin blocks of 19 cases of low grade and 21 cases of high grade mucoepidermoid carcinoma were selected and stained by toluidine blue.The number of mast cells were observed in two manners(absolute and ordinal).T student was used for absolute counting and Mann Whitney for ordinal counting. in absolute counting,we defined a number for counting, for ordinal counting, we defined an interval range for mast cell numbers. Results. In absolute Counting,the mean of mast cell density in low grade cases was 19.7+/-15.7and in high grade cases was 20.3+/-21.07and there was no significant difference between two groups(p=0.920). In ordinal counting, there was no significant difference between two groups in mast cell density(p=0.729). Conclusion. According to this study, the mast cell counting can not be used for histopathological grading of MEC
Mast Cell, Histopathological Grading, Mucoepidermoid Carcinoma
To cite this article
Farzad Yazdani, Gita Rezvani, Sajad Safari, Maryam Jaberi, Histop Athological Comparision of Mast Cell Density in Various Grades of Mucoepidermoid Carcinoma, Cancer Research Journal. Vol. 3, No. 5, 2015, pp. 100-103. doi: 10.11648/j.crj.20150305.12
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