Volume 8, Issue 4, December 2020, Page: 62-67
Primitive Neuroectodermal Tumor of Cervix: Report of a Rare Case and Review of Literature
Rajendra Kumar Tanwar, Department of Radiation Oncology, Government Medical College, Kota, Rajasthan University of Health Sciences, Jaipur, Rajasthan, India
Bharti Saxena, Department of Obstetrics and Gynecology, Government Medical College, Kota, Rajasthan University of Health Sciences, Jaipur, Rajasthan, India
Harsh Goyal, Department of Radiation Oncology, Government Medical College, Kota, Rajasthan University of Health Sciences, Jaipur, Rajasthan, India
Shagufta Siddiqui, Department of Obstetrics and Gynecology, Government Medical College, Kota, Rajasthan University of Health Sciences, Jaipur, Rajasthan, India
Rakesh Kumar Singh, Department of Pathology, Government Medical College, Kota, Rajasthan University of Health Sciences, Jaipur, Rajasthan, India
Ravindra Singh Gothwal, Department of Radiation Oncology, Government Medical College, Kota, Rajasthan University of Health Sciences, Jaipur, Rajasthan, India; Department of Radiation Oncology, SMS Medical College, Jaipur, Rajasthan University of Health Sciences, Jaipur, Rajasthan, India
Madhu Saxena, Department of Anesthesiology, Government Medical College, Kota, Rajasthan University of Health Sciences, Jaipur, Rajasthan, India
Received: Oct. 25, 2020;       Accepted: Nov. 5, 2020;       Published: Nov. 16, 2020
DOI: 10.11648/j.crj.20200804.12      View  22      Downloads  28
Abstract
Background – Primitive neurocetodermal tumor / Ewing’s sarcoma (PNET/ES) of uterine cervix is extremely rare tumor and only 27 cases have so far been reported in the literature. We hereby present one case report diagnosed by histopathology and IHC and review of literature. Objective –A young girl aged 20 years was admitted. Her routine investigations and CT and MRI scan of chest, abdomen and pelvis were performed. Biopsy was taken from vaginal mass and histopathologist reported as round cell tumor. The slides were reviewed by another pathologist and found to be rhabdomyosarcoma. Thus immunohistopathology was done and a diagnosis of PNET/ES was established. Methods – The patient presented with complains of vaginal bleeding, generalized body ache, poor nutritional intake, found extensive loco regional disease with metastases to liver, lung and multiple bones, stage FIGO IV, performance score ECOG -4. Owing to her low general condition, we could not plan any anti-cancer treatment like chemotherapy or radiation therapy. She was discharged on symptomatic treatment. Results – Her biopsy and immunohistopathology turn out to be PNET/ES of uterine cervix. Conclusion - The rarity of this entity poses a challenge to pathologists and oncologists. The PNET/ES of uterine cervix can be potentially curable if presented at an early stage and found operable. IHC plays an important role in establishing this rare diagnosis.
Keywords
PNET, PNET Cervix Uteri, Immunohistochemistry, Peripheral, Neuroepithelioma, Uterine Cervix
To cite this article
Rajendra Kumar Tanwar, Bharti Saxena, Harsh Goyal, Shagufta Siddiqui, Rakesh Kumar Singh, Ravindra Singh Gothwal, Madhu Saxena, Primitive Neuroectodermal Tumor of Cervix: Report of a Rare Case and Review of Literature, Cancer Research Journal. Vol. 8, No. 4, 2020, pp. 62-67. doi: 10.11648/j.crj.20200804.12
Copyright
Copyright © 2020 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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