Cancer Research Journal

Volume 5, Issue 4, July 2017

  • Regulation of HepG2 Fat Metabolism by IL1β and IL1 Receptor Antagonist

    Susmita Chandra

    Issue: Volume 5, Issue 4, July 2017
    Pages: 24-34
    Received: 7 December 2017
    Accepted: 22 December 2017
    Published: 16 January 2018
    Abstract: Non-alcoholic fatty liver disease (NAFLD) is the major cause of steatohepatitis, cirrhosis and hepatocellular carcinoma. High saturated fat rich diet is one of the known causes of NAFLD. Non-Alcoholic liver disease NAFLD is characterized by steatosis and upregulation of different proinflammatory cytokines, like caspase-1 dependant IL1β, type I IL1 ... Show More