Cancer Research Journal

Volume 6, Issue 2, June 2018

  • Comparative Antiproliferative Activity of Leaf and Stem Bark Extracts of Detarium senegalense and Leaf of Cymbopogon citratus

    Francis Agada, Chika Muhammad, Ahmad Uba, Halilu Emmanuel Mshelia, Halima Lawal Zubairu

    Issue: Volume 6, Issue 2, June 2018
    Pages: 38-46
    Received: Jan. 13, 2018
    Accepted: Jan. 29, 2018
    Published: Mar. 07, 2018
    Downloads:
    Views:
    Abstract: Malignant cancer cells exhibit uncontrollable high proliferation similarly to meristematic cells of seeds, this led to the establishment that agents capable of producing antiproliferative effects are potential anticancer agents. The experimental plant used for this research was Sorghum bicolor seeds. The sole aim of this research work is to unveil ... Show More
  • The Expression and Significance of STAT6, VEGF and MVD in Nasal Polyps

    Qingsong Cao, Jie Zhang

    Issue: Volume 6, Issue 2, June 2018
    Pages: 47-50
    Received: Feb. 15, 2018
    Accepted: Mar. 01, 2018
    Published: Mar. 22, 2018
    Downloads:
    Views:
    Abstract: The aim of the current study was to evaluate the expression levels of STAT6, VEGF and microvessel density (MVD) score in nasal polyp tissues and to explore the underlying relationships during the pathogenesis of nasal polyps. 40 cases with surgical removal of nasal polyps were included, comparing with control group of 10 inferior turbinate mucosal ... Show More
  • N-Nitrosation of Dimethylamine by Bacillus cereus Isolated from Fermented Palm Sap (Elaeis guineensis)

    Adeleke G. E., Adedosu O. T., Oyewo E. B., Fatoki J. O., Abioye D. H., Ishola A. A., Maduagwu E. N.

    Issue: Volume 6, Issue 2, June 2018
    Pages: 51-61
    Received: Dec. 31, 2017
    Accepted: Mar. 05, 2018
    Published: Mar. 27, 2018
    Downloads:
    Views:
    Abstract: This study investigated the nitrosating activities of intact cells and cell fractions of Bacillus cereus isolated from fermented palm wine (Elaeis guineensis) during incubation with dimethylamine and nitrite or nitrate. The pH values of the incubation mixtures were 7.2 ± 0.07 and 7.1 ± 0.07 in the presence of nitrite and nitrate, respectively. The ... Show More
  • Prediction and Depiction of Potential RNA-Based Therapeutics for Oncogenic E6 and E7 Genes of Human Papilloma Virus Types 16 & 18: A New Class of Treatment for Lung Cancer

    Moinul Abedin Shuvo, Sayeedul Alam Prince, Arifuzzaman

    Issue: Volume 6, Issue 2, June 2018
    Pages: 62-69
    Received: Feb. 02, 2018
    Accepted: Feb. 25, 2018
    Published: Apr. 02, 2018
    Downloads:
    Views:
    Abstract: Unlike almost all the cervical, penile, vulvar, and anal cancers, where Human papilloma virus has long known to play a vital role, a causative link between carcinogenic Human papilloma virus and lung cancer have been found to be highly variable and contradictory. Data also shows geography and race-dependenty. Apart from etiological factors, viral c... Show More
  • Extensive Bone Lesions and Skin Lesions Revealing an Acute Transformation of an Extramedullary Chronic Myeloid Leukemia

    Bienvenu Houssou, Mouna Lamchahab, Halima Hadri, Boubker Messoudi, Abdeljabbar Messoudi, Asma Quessar

    Issue: Volume 6, Issue 2, June 2018
    Pages: 70-73
    Received: Mar. 13, 2018
    Accepted: Mar. 29, 2018
    Published: May 05, 2018
    Downloads:
    Views:
    Abstract: Extramedullary blast transformation as the initial presentation of Chronic Myeloid Leukemia with bone marrow remaining in the chronic phase is an unusual event. We report the case of a 30-year-old with chronic CML at the medullary level and an acute transformation revealed by extensive bone lyses and skin lesions. A 30-year-old man had cutaneous no... Show More