Cancer Research Journal

Volume 6, Issue 4, December 2018

  • Hsa-miR-106b-5p Negatively Regulates LEF1

    Annada Anil Joshi, Alka Vishwas Nerurkar, Neelam Vishwanath Shirsat

    Issue: Volume 6, Issue 4, December 2018
    Pages: 112-117
    Received: 23 August 2018
    Accepted: 10 September 2018
    Published: 13 October 2018
    DOI: 10.11648/j.crj.20180604.11
    Abstract: Aberrant expression of the genes involved in Wnt signaling pathway, one of the most important developing pathways, is observed in many malignancies. Reports show that Wnt/β-catenin activation is critical for cancer development, angiogenesis, migration, and invasion. LEF1 belongs to the T cell Factor (TCF)/LEF family of transcription factors and pla... Show More
  • Clinico-Epidemiological Study of Epithelial Ovarian Cancer Mansoura Experience

    Soumaya Mohamed Eteba, Maiy Abdul-Raheim Alshahat, Fatma Mohamed Farouk Akl, Nehal Kadry Mohammed

    Issue: Volume 6, Issue 4, December 2018
    Pages: 118-125
    Received: 15 November 2018
    Accepted: 5 December 2018
    Published: 18 December 2018
    DOI: 10.11648/j.crj.20180604.12
    Abstract: Background & objective: Ovarian cancer is the fifth most common cancer affecting women today. The aim of this retrospective study was to present the epidemiological, pathological, clinical characteristics of epithelial ovarian cancer patients treated at Clinical Oncology and Nuclear Medicine Department, Mansoura University Hospitals in the period b... Show More