Cancer Research Journal

Volume 9, Issue 3, September 2021

  • Spectrum of HIV Associated Malignancies: A Retrospective Study of 42 Patients over a Period of 16 Years Attending a Tertiary Care Hospital

    Rajendra Kumar Tanwar, Bharti Saxena, Manu Singh Tanwar, Abhirup Chatterjee, Harsh Goyal, Naveen Saxena, Raghuveer Singh, Madhu Saxena, Uma Shankar Shukla

    Issue: Volume 9, Issue 3, September 2021
    Pages: 131-139
    Received: Jun. 15, 2021
    Accepted: Jun. 30, 2021
    Published: Jul. 07, 2021
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    Abstract: Introduction: The Human immunodeficiency virus (HIV) infection remains a serious public health concern in India and around the world at large. Malignancy is frequent among people living with HIV (PLWH) has become the leading cause of death. The incidence of malignancy among PLWH depends on various factors; virological control under combined antiret... Show More
  • Prognostic Significance of Platelet-to-Lymphocyte Ratio in Gliomas: A Meta-analysis

    Huayue Cong, Aixia Sui, Liuyi Yang, Huiling Song, Jing Zhao, Yong Liu, Mingming Zhang, Weiliang He

    Issue: Volume 9, Issue 3, September 2021
    Pages: 140-147
    Received: Jun. 20, 2021
    Accepted: Jun. 30, 2021
    Published: Jul. 07, 2021
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    Abstract: Background and objective: Inflammatory factors are associated with tumour initiation, progression, invasion, and metastasis. It is a potential prognostic factor for multiple solid tumours. Such as cholangiocarcinoma, bladder cancer, nasopharyngeal carcinoma and so on. However, there is no clear evidence that elevation of the systemic inflammatory m... Show More
  • A Preliminary Study on Lung Cancer Prevalence Among Patients with Tuberculosis in Lesotho

    Mopa Alina Sooro, Thibello Malikelle, Refiloe Leteka, Lejeremane Kobo, Maseabata Ramathebane

    Issue: Volume 9, Issue 3, September 2021
    Pages: 148-153
    Received: Jun. 18, 2021
    Accepted: Jun. 29, 2021
    Published: Jul. 13, 2021
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    Abstract: Tuberculosis (TB) is one of the major causes of ill health associated with infection in approximately a quarter of the global population. Lesotho has been ranked among the top 30 high TB burden countries; however the prevalence of lung cancer in Lesotho has been ranked fifth among the top 5 cancers in men. This seemingly lower prevalence of lung ca... Show More
  • To Explore the Mechanism of Prunella Vulgaris on Lymphoma Based on Network Pharmacology and Molecular Docking

    Xiaohong Wu, Huiling Song, Aixia Sui, Xinyu Zhao, Hongtao Zhang

    Issue: Volume 9, Issue 3, September 2021
    Pages: 154-161
    Received: Jun. 22, 2021
    Accepted: Jul. 02, 2021
    Published: Jul. 13, 2021
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    Abstract: Background. Although the traditional Chinese medicine Prunella vulgaris may be effective in treating lymphoma, its mechanism of action remains unclear. The purpose of this paper is to explore the mechanism of Prunella vulgaris against lymphoma by combining network pharmacology and molecular docking. Methods. The potential active ingredients of Prun... Show More
  • Carcinoid Syndrome in a Patient with Duodenal Carcinoid Tumor

    Khan Mohammad Nazmus Saqeb, Fariah Sharmeen, Farzana Hafiz

    Issue: Volume 9, Issue 3, September 2021
    Pages: 162-165
    Received: Jul. 10, 2021
    Accepted: Jul. 27, 2021
    Published: Aug. 04, 2021
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    Abstract: Duodenal carcinoid tumors accounts for 5% of all Gastrointestinal Neuroendocrine Tumors (GI-NETs). Only 4% of all duodenal carcinoid tumors present with a full-blown carcinoid syndrome. We report a case of duodenal carcinoid tumor presenting as carcinoid syndrome in a 58 year old man, who presented with upper abdominal discomfort, diarrhoea, hot fl... Show More
  • Paclitaxel Based CCRT Is an Acceptable Alternative for Cisplatin Based CCRT in the Treatment of Locally Advanced (Stage IVA) Head Neck Carcinoma

    Md. Zillur Rahman Bhuiyan, Rokaya Sultana, Ranjan Kumar Bhoumic, Sayed Farhan Ali Razib, Ashish Kumar Shaha, Ariful Haque

    Issue: Volume 9, Issue 3, September 2021
    Pages: 166-170
    Received: Aug. 03, 2021
    Accepted: Aug. 12, 2021
    Published: Aug. 24, 2021
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    Abstract: Introduction: Head neck carcinoma is the sixth most common cancer in the world. Concurrent chemo radiation became standard protocol for patients with locally advanced squamous cell carcinoma of head neck where curable surgery is not feasible. Study Design and Objective: This quasiexperimental study done to compare the treatment response and acute t... Show More
  • A Phase 1 Dose Escalation Study of Eribulin in Combination with Weekly Carboplatin for the Treatment of Metastatic Breast Cancer

    Aixa Elena Soyano, Michael Shafique, Roohi Ismail-Khan, Dawn Goodridge, David Boulware, Hatem Soliman, Hyo Sook Han

    Issue: Volume 9, Issue 3, September 2021
    Pages: 171-175
    Received: Aug. 02, 2021
    Accepted: Aug. 24, 2021
    Published: Aug. 31, 2021
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    Abstract: Background: Metastatic breast cancer is a common and devastating diagnosis. New strategies for treatment are needed to help improve outcomes. Eribulin is an anti-microtubule agent approved in 2010 for advanced breast cancer. Combination with other chemotherapeutic agents provides an alternative treatment option for these patients. Purpose: This stu... Show More