Cancer Research Journal

Volume 10, Issue 2, June 2022

  • Analysis of the Efficacy of Anlotinib in the Late-Line Treatment of Advanced Leiomyosarcoma: A Case Report

    Tai Zhao, Yajin Wang, Yuqing Du

    Issue: Volume 10, Issue 2, June 2022
    Pages: 26-29
    Received: Feb. 15, 2022
    Accepted: Mar. 15, 2022
    Published: Apr. 14, 2022
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    Abstract: Primary retroperitoneal leiomyosarcoma originated from smooth muscle tissue or mesenchymal cells with the potential to differentiate into smooth muscle cells, showing aggressive growth, easy to recur and metastasize after operation, with a 5-year overall survival rate of 28% - 40%. Multidisciplinary comprehensive treatment based on surgery is an ef... Show More
  • Prognostic Significance of Systemic Cholesterol Profile in Patients with Breast Cancer

    Radhika Chowdary, Raghu Ram Pillarisetti, Vinod Kumar Verma, Radhika Korabathina, Syed Sultan Beevi

    Issue: Volume 10, Issue 2, June 2022
    Pages: 30-33
    Received: Mar. 28, 2022
    Accepted: Apr. 15, 2022
    Published: Apr. 25, 2022
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    Abstract: Breast cancer ranks as the number one cancer among Indian females with survival as low as 66.1%. Relationship between cholesterol and breast cancer has triggered special interest due to their role in important cellular processes that steer toward carcinogenesis. The interplay between cholesterol and tumor development have been studied in experiment... Show More
  • Sarcomatoid Carcinoma of the Gallbladder: A Case Report and Literature Review

    Ting Xiong, Shihua Liu, Yuying Lei, Liangliang Zhang, Aixia Sui

    Issue: Volume 10, Issue 2, June 2022
    Pages: 34-37
    Received: May 14, 2022
    Accepted: Jun. 02, 2022
    Published: Jun. 14, 2022
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    Abstract: Sarcomatoid carcinoma of the gallbladder is a highly malignant tumor originating from totipotent mesenchymal stem cells, accounting for only 4.1% of gallbladder cancers. Its clinical manifestations are very similar to adenocarcinoma of the gallbladder, mainly presenting in the digestive tract. Surgical resection is currently the only possible cure ... Show More
  • Application and Research Status of 125I Seeds Brachytherapy in Unresectable Pancreatic Cancer

    Xinxin Duan, Liuyi Yang, Jie Zhou, Ting Xiong, Aixia Sui

    Issue: Volume 10, Issue 2, June 2022
    Pages: 38-45
    Received: Jun. 02, 2022
    Accepted: Jun. 16, 2022
    Published: Jun. 27, 2022
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    Abstract: Pancreatic cancer is a digestive system tumor with high degree of malignancy. At present, systemic chemotherapy is the main treatment method. However, due to the difficulty in early diagnosis and easy spread of pancreatic cancer, the survival cycle of patients is short and the treatment effect is poor. 125I seed brachytherapy has obvious advantages... Show More
  • The Role of DLL4-Notch-VEGFR2 Signaling Pathway in Tumor Angiogenesis

    Jie Zhou, Xinxin Duan, Ting Xiong, Aixia Sui

    Issue: Volume 10, Issue 2, June 2022
    Pages: 46-50
    Received: Jun. 03, 2022
    Accepted: Jun. 17, 2022
    Published: Jun. 27, 2022
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    Abstract: Tumor angiogenesis is the center of tumor growth and metastasis, and it increases the supply of nutrients and oxygen to tumors, thereby supporting tumor growth and progression. Vascular endothelial growth factor (VEGF) is a stimulator of angiogenesis and also plays a key role in the process of angiogenesis. Overexpression of VEGF is associated with... Show More
  • Warthin Tumor of Parotid Gland Complicated with Hyperhematuria Amylase: A Case Report and Literature Review

    Leiqing Bu, Yupeng Yang, Huan Mi, Chenyu Zhang, Jianqi Gu

    Issue: Volume 10, Issue 2, June 2022
    Pages: 51-54
    Received: Jun. 03, 2022
    Accepted: Jun. 17, 2022
    Published: Jun. 27, 2022
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    Abstract: Clinically, there are many reasons for the elevation of hematuria amylase, the most common being mumps and acute pancreatitis, but it is rare for parotid gland masses to be associated with elevated hematuria amylase. Reading the literature, it can be found that there are few reports about parotid gland tumors and increased hematuria amylase. Most o... Show More